In rocket science, the Tyranny of the Rocket Equation refers to the fact that there is a limit to the amount of payload a rocket can carry, as the heavier the payload, the more rocket fuel that is needed to carry the payload.
So trying to add more weight to a rocket’s payload will require more fuel, which adds more weight to a rocket’s payload, which will require more fuel, which adds more to a rocket’s payload, which will require more fuel…
In practice, this means that there is a limit to how much a rocket can carry, and how far it can travel.